Abstract: Various extracts of Rauvolfia serpentina fruit evaluated for antibacterial and antifungal activity. The experimental methods were used cup plate method at a dose 1 mg/ml. Among the various extracts the water and chloroform extract showed good activity against bacterial strains E. coli and P. Klebsilla and remaining Pet. ether and Ethanol extract also showed good activity against P. aeruginosa and S. aureus. The various extracts of Rauvolfia serpentina were studied for antifungal activity among various extracts the Pet. Ether and Ehtanol extract showd good activity against A.flavus and A. niger and remaining extracts showed poor to moderate activity. All extracts of fruit subjected to Antimicrobial screening and the results are tabulated in Table (1) and (2).

Keywords: Rauvolfia serpentina, Antifungal, Antibacterial Screening.