Abstract: Glutaminase is one of the most important commercially produced industrial enzyme. Among its industrial applications it is used in dairy, fermentaed sauce production, vitamin B6 production, biosencer. The role of glutaminase as antileukamic and as food flavoring agent is established. The list of both the industrial and therapeutic uses of glutaminase is increasing continuously. Glutaminase has shown its profound effect an antiviral activity and HIV associated dementia and multiple sclerosis. The present review discusses some of important proven uses and some yet to be commercially established application of glutaminase.

Keywords: L-glutaminase, food flavor, Glutamine, Glutamic acid, Antileukamic, anti HIV.