Abstract: Pseudomonas spp. is one of the foremost etiological agent causing severe infections of hospital admitted patients. This study was carried out to monitor the drug sensitivity patterns of the phenotypically identified Pseudomonas spp. collected from a nmber of admired diagnostic centers of Dhaka city, Bangladesh. A total of 50 non-duplicate isolates were characterized from various patients having diverse age groups and sex. The microorganisms found from varied specimens (i.e. urine, pus, sputum, ear secretions, wound swabs) were identified by a number of phenotypic and biochemical tests. Antibiotic susceptibility patterns against 20 different antibiotics were evaluated by the Agar-disc-diffusion method to comprehend antibiotic resistance profile of the isolates. All the isolates were presumptively detected as Pseudomonas spp. The female patients (68%) were likely to be more susceptible to the infections caused by Pseudomonas spp. than their male counterparts (32%). Most of isoltaes showed multi-drug resistant (MDR) property. The highest resistance was recorded against amoxyclav 100%, nitrofurantion 100%, cotrimoxazole 100%, cefuroxime 98%, azithromycin 92 %, ceftriaxone 86%, tygecycline 78% and nalidixic acid 70%. Thee findings of this study showed that colistin was the most effective drug for the inhibition of Pseudomonas spp. followed by piperacillin, meropenem and amikacin.

Keywords: Pseudomonas spp., multi-drug resistant, effective drug.

| DOI: 10.17148/IARJSET.2020.71201