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          International Advanced Research Journal in             Science, Engineering and Technology

A monthly Peer-reviewed / Refereed journal

ISSN Online 2393-8021
ISSN Print 2394-1588

Since  2014

Detection of the Prevalence of Etiological Agents of Enteric Fever through Triple-Antigen Tests in the Northern Part of Bangladesh

Mehjabin Ferdous, Md.Suzaul Alam, Jannatul Ferdose Supti, Tasnim Jabin, Md. Mobarak Hossain, Sawda Binte Monir, Md Aftab Uddin*

Abstract: Highly virulent Salmonella enterica serovars (Typhi and Paratyphi) is the leading cause of typhoid fever and sufferings of enteric fever worldwide and due to this, about 16.6 million infections and 1.6 million deaths are estimated in the world each year. Due to the wide variety of clinical manifestations demonstrated by the pathogen, it can be considered challenging to diagnose it. Several diagnostic techniques are employed throughout South Asia, including Bangladesh, one of which is the Triple Antigen Test.

The purpose of this study was to apply this technique to determine the prevalence of enteric fever in North Bengal, Bangladesh. A total of 176 blood specimens were examined for Salmonella Typhi/Paratyphi (Widal test); Proteus species, rickettsial infections (Weil Felix test), and brucellosis (Brucella antibody test). Overall, 64.04% showed positive results for enteric fever. The results identified Salmonella enterica serovars Typhi to be the most prevalent agent, with no Paratyphi or brucellosis cases detected. However, dependence on serology-based testing without antibiogram profiling is inadequate for diagnosis and treatment. Widal test findings can be challenging to interpret due to previous antibiotic treatment and the possibility of false negative results. Improved diagnostic techniques like Typhidot RDT, IgM StripTest, IDL TUBEX Test, and fast stool culture are required for accurate estimations of enteric fever, in addition to following the standards of World Health Organization (WHO) and the Center for Disease Prevention and Control (CDC).

Keywords: Enteric fever, Salmonella enterica, Typhi, Paratyphi, Widal test, Weil felix test.

Cite:
Mehjabin Ferdous, Md.Suzaul Alam, Jannatul Ferdose Supti, Tasnim Jabin, Md. Mobarak Hossain, Sawda Binte Monir, Md Aftab Uddin*,"Detection of the Prevalence of Etiological Agents of Enteric Fever through Triple-Antigen Tests in the Northern Part of Bangladesh", IARJSET International Advanced Research Journal in Science, Engineering and Technology, vol. 11, no. 2, 2024, Crossref https://doi.org/10.17148/IARJSET.2024.11211.


PDF | DOI: 10.17148/IARJSET.2024.11211

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