Abstract: Aims: In the present study, an ethanolic leaves extract of Moringa Oleifera was examined for its antiulcer potential in experimental albino rats using two models: ethanol induced and pylorus ligation-induced gastric ulceration. The extract was orally administered at three different doses (100, 150, and 250mg/kg) for 15 consecutive days. The anti-ulcer effect in rats treated with different doses of Moringa oleifera leaves extract and omeprazole (30 mg/kg, p.o.). The study was carried out between November 2020 to February 2021 in the Pharmacology Laboratory of Department of Pharmacology. Bharat Technology, West Bengal, India, Methodology: The ethanol leaf extract of Moringa Oleifera was prepared. The doses of the extract administered to the rats were 100,150, 250 mg/kg body weight respective, Ulcer was induced with diclofenac sodium (100mg/kg; b.w.). omeprazole (30 mg/kg, p.o.) were determined and statistically compared with the anti-ulcer effects in the control rats treated with saline (NaCl, 0.9%). The MO at doses of 100, 150 and 250 mg/kg decreased the ulcer index significantly as compared to the control group (p


Downloads: PDF | DOI: 10.17148/IARJSET.2021.8599

How to Cite:

[1] Preeti Sah*, Md. Kabirul Islam Mollah, Bidisha Roy, "Evaluation of the Effect of Moringa oleifera on Diclofenac Sodium Induced Ulcer in Male Wistar Rats," International Advanced Research Journal in Science, Engineering and Technology (IARJSET), DOI: IARJSET.2021.8599

Open chat