Abstract: The haemostatic and wound healing activity of Mikania micrantha Leaves was investigated on wistar rats. Place and Duration of Study: The study was carried out between October 2020 and February 2021 in the Pharmacology, Bharat Technology, West Bengal, India. The aquous extract of Mikania micrantha was prepared. The doses of the aquous extract administered to the wistar rats was 70 mg/kg body weight respective, and wound healing was induced with fusidic acid (15mg/kg; b.w.), N-Tranexamic acid (5 mg/kg; b.w.). The haemostatic and Wound Healing activity was assessed by the Mikania micrantha extract. The aquous extract of sample showed a significant wound healing activity of aquous extract on excision wound model also showed a significant(10-12days) where Fusidic acid completely cure the wistar rats approximately 11 days for haemostatis activity N-Tranexamic acid work approximately(2-3minutes) where aquous extract work 3-4 min.

Keywords: Mikania micrantha leaves, Haemostatic, Wound healing, Fusidic acid, N-Tranexamic acid.


PDF | DOI: 10.17148/IARJSET.2021.8699

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