Abstract: World human population is increasing with an alarming rate; and a variety of new types of health issues are popping up. For instance, increase in number of drug-resistant bacteria is a cause of concern. Research on antibiotics and other microbial natural products is pivotal in the global fight against the growing problem of antibiotic resistance. It is necessary to find new antibiotics to tackle this problem. The use of therapeutic plant species in traditional medicine is as old as mankind; and currently, it is strongly believed that all types of plant species across the plant kingdom do harbour Endophytic Bacteria (EB). The Endophytes derived natural products such as Ecomycins, Pseudomycins, Munumbicins and Xiamycins are antibacterial, antimycotic and antiplasmodial. Some of these natural products have been reported to possess even antiviral (including Human Immunodeficiency Virus (HIV) properties. Ndophyrtic bacteria could serve as a potential source of novel antibiotics. This study aimed to isolate and characterize plant Endophytes and antimicrobial activity of endophyte was investigated against selected pathogenic strains.

Keywords: Antibiotics, Endophytes, Antibacterial, Antimycotic

| DOI: 10.17148/IARJSET.2020.7205