Abstract: The pharmaceutical sector in India is undergoing a paradigm shift, driven by rapid digitization and increasing internet penetration. E-pharmacies online platforms facilitating the sale of medicines have emerged as a significant disruptor, promising accessibility, affordability, and convenience. However, this burgeoning sector operates within a complex ecosystem fraught with challenges. This paper explores the multifaceted hurdles facing e-pharmacies in India, categorized into regulatory ambiguity, operational logistics, patient safety concerns, and the socio-economic conflict with traditional brick-and-mortar retailers. Through an analysis of the current legal framework and market dynamics, this study argues that while e-pharmacies hold immense potential for public health, a robust and clear regulatory mechanism is a prerequisite for sustainable growth.

Downloads: | DOI: 10.17148/IARJSET.2025.121209