Abstract: The marine environment is an extremely complex ecosystem and contains a broad spectrum of fungal diversity. Marine fungi were isolated from water and sediment samples from different sites. Fungal isolates were recovered and morphologically most of the strains belonged to the fungal genera such as Aspergillus and Penicillium. Antimicrobial substance from marine fungi was produced by agar plate method. The potent fungal were inoculated on production medium and extracted was done. The extracted compound was checked for antimicrobial activity against microbial pathogens such as Bacillus subtilis, Escherichia coli, Klebsiella aerogenes, Staphylococcus aureus etc. The results showed maximum zone against E. coli. In most of the researches, strains belonging to fungal genre Aspergillus (Aspergillus niger, Aspergillus welwitschiae) as potential candidate offering a better scope for the production, purification and isolation of broad spectrum antimicrobial compound.

Keywords: Marine fungi, antimicrobial activity, secondary metabolites, microbial pathogens, Aspergillus

| DOI: 10.17148/IARJSET.2021.8454