Abstract: In this present work β-Lactam was synthesized through a 2-((4-chlorophenyl) (piperidin-4-yloxy) methyl) pyridine, bromoethyl acetate, hydrazine hydrate, substituted aldehyde to obtain Schiff base derivatives by using glacial Acetic acid in ethanol. Further Cyclization of Shiff bases with Chloroacetyl chloride in the presence of triethyl amine give the corresponding β-lactam derivatives. All these compounds identified by (FTIR ,1H-NMR, 13C-NMR) and follow by (TLC) and melting points of them.

Keywords: 2-((4-chlorophenyl) (piperidin-4-yloxy) methyl) pyridine, Schiff base, Heterocyclic compound, β-Lactam derivative.

| DOI: 10.17148/IARJSET.2025.12222